Arsenic trioxide induces autophagic degradation of the FLT3-ITD mutated protein in FLT3-ITD acute myeloid leukemia cells

The prognosis of acute myeloid leukemia (AML) with FMS-like tyrosine kinase 3 internal tandem duplication (FLT3-ITD) mutations is poor. Some studies, including our previous study, have indicated that arsenic trioxide (ATO) exhibited significant anti-carcinogenic activity in FLT3-ITD AML cells and ex...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Cancer
Auteurs principaux: Liu, Xiao-Jian, Wang, Li-Na, Zhang, Zu-Han, Liang, Cong, Li, Yu, Luo, Jie-Si, Peng, Chun-Jin, Zhang, Xiao-Li, Ke, Zhi-Yong, Huang, Li-Bin, Tang, Yan-Lai, Luo, Xue-Qun
Format: Artigo
Langue:Inglês
Publié: Ivyspring International Publisher 2020
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7150460/
https://ncbi.nlm.nih.gov/pubmed/32284743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.29751
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