A dual inhibitor overcomes drug-resistant FLT3-ITD acute myeloid leukemia

FLT3 mutations are the most frequently identified genetic alterations in acute myeloid leukemia (AML) and are associated with poor prognosis. Multiple FLT3 inhibitors are in various stages of clinical evaluation. However, resistance to FLT3 inhibitors resulting from acquired point mutations in tyros...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Hematol Oncol
Egile Nagusiak: Wang, Peihong, Xiao, Xinhua, Zhang, Yuyin, Zhang, Baoyuan, Li, Donghe, Liu, Mingzhu, Xie, Xi, Liu, Chenxuan, Liu, Ping, Ren, Ruibao
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2021
Gaiak:
Letter to the Editor
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8255005/
https://ncbi.nlm.nih.gov/pubmed/34217323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-021-01098-y
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