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Novel AXL-targeted agents overcome FLT3 inhibitor resistance in FLT3-ITD(+) acute myeloid leukemia cells

AXL receptor tyrosine kinase (AXL) upregulation mediates drug resistance in several types of human cancer and has become a therapeutic target worthy of exploration. The present study investigated AXL antigen expression and the effects of novel AXL-targeted agents in acute myeloid leukemia (AML) cell...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Liu, Yi, Wei, Jing, Liu, Jiaxin, Ma, Weina, Duan, Yanting, Liu, Daihong
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7988696/
https://ncbi.nlm.nih.gov/pubmed/33777220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2021.12658
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