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Oncogenic roles of PRL-3 in FLT3-ITD induced acute myeloid leukaemia
FLT3-ITD mutations are prevalent mutations in acute myeloid leukaemia (AML). PRL-3, a metastasis-associated phosphatase, is a downstream target of FLT3-ITD. This study investigates the regulation and function of PRL-3 in leukaemia cell lines and AML patients associated with FLT3-ITD mutations. PRL-3...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Blackwell Publishing Ltd
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3799491/ https://ncbi.nlm.nih.gov/pubmed/23929599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201202183 |
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