DIFFERENTIAL EXTRACELLULAR, BUT SIMILAR INTRACELLULAR, DISPOSITION OF TWO TENOFOVIR FORMULATIONS IN THE MALE GENITAL TRACT

BACKGROUND: The male genital tract (MGT) is a viral sanctuary and likely HIV reservoir; understanding MGT pharmacokinetics (PK) of antiretrovirals (ARVs) used for curative strategies is critical to eradication and cure. Tenofovir alafenamide (TAF) is a tenofovir (TFV) formulation designed to maximiz...

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Bibliografiset tiedot
Julkaisussa:Antivir Ther
Päätekijät: DUMOND, JULIE B., GREENE, STEPHEN A., PRINCE, HEATHER M.A., CHEN, JINGXIAN, MAAS, BRIAN L., SYKES, CRAIG, SCHAUER, AMANDA P., BLAKE, KIMBERLY, NELSON, JULIE A.E., GAY, CYNTHIA L., KASHUBA, ANGELA D.M., COHEN, MYRON S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2019
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7147147/
https://ncbi.nlm.nih.gov/pubmed/30375984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3851/IMP3277
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