DIFFERENTIAL EXTRACELLULAR, BUT SIMILAR INTRACELLULAR, DISPOSITION OF TWO TENOFOVIR FORMULATIONS IN THE MALE GENITAL TRACT

BACKGROUND: The male genital tract (MGT) is a viral sanctuary and likely HIV reservoir; understanding MGT pharmacokinetics (PK) of antiretrovirals (ARVs) used for curative strategies is critical to eradication and cure. Tenofovir alafenamide (TAF) is a tenofovir (TFV) formulation designed to maximiz...

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Détails bibliographiques
Publié dans:Antivir Ther
Auteurs principaux: DUMOND, JULIE B., GREENE, STEPHEN A., PRINCE, HEATHER M.A., CHEN, JINGXIAN, MAAS, BRIAN L., SYKES, CRAIG, SCHAUER, AMANDA P., BLAKE, KIMBERLY, NELSON, JULIE A.E., GAY, CYNTHIA L., KASHUBA, ANGELA D.M., COHEN, MYRON S.
Format: Artigo
Langue:Inglês
Publié: 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7147147/
https://ncbi.nlm.nih.gov/pubmed/30375984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3851/IMP3277
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