DIFFERENTIAL EXTRACELLULAR, BUT SIMILAR INTRACELLULAR, DISPOSITION OF TWO TENOFOVIR FORMULATIONS IN THE MALE GENITAL TRACT

BACKGROUND: The male genital tract (MGT) is a viral sanctuary and likely HIV reservoir; understanding MGT pharmacokinetics (PK) of antiretrovirals (ARVs) used for curative strategies is critical to eradication and cure. Tenofovir alafenamide (TAF) is a tenofovir (TFV) formulation designed to maximiz...

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Udgivet i:Antivir Ther
Main Authors: DUMOND, JULIE B., GREENE, STEPHEN A., PRINCE, HEATHER M.A., CHEN, JINGXIAN, MAAS, BRIAN L., SYKES, CRAIG, SCHAUER, AMANDA P., BLAKE, KIMBERLY, NELSON, JULIE A.E., GAY, CYNTHIA L., KASHUBA, ANGELA D.M., COHEN, MYRON S.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7147147/
https://ncbi.nlm.nih.gov/pubmed/30375984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3851/IMP3277
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