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Wapl releases Scc1-cohesin and regulates chromosome structure and segregation in mouse oocytes
Cohesin is essential for genome folding and inheritance. In somatic cells, these functions are both mediated by Scc1-cohesin, which in mitosis is released from chromosomes by Wapl and separase. In mammalian oocytes, cohesion is mediated by Rec8-cohesin. Scc1 is expressed but neither required nor suf...
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| Publicado no: | J Cell Biol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Rockefeller University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7147110/ https://ncbi.nlm.nih.gov/pubmed/32328639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201906100 |
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