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Wapl is an essential regulator of chromatin structure and chromosome segregation
Mammalian genomes contain several billion base pairs of DNA which are packaged in chromatin fibers. At selected gene loci, cohesin complexes have been proposed to arrange these fibers into higher-order structures (1–7) but it is poorly understood how important this function is for determining overal...
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| Publicat a: | Nature |
|---|---|
| Autors principals: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6080692/ https://ncbi.nlm.nih.gov/pubmed/23975099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12471 |
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