Native Zinc Catalyzes Selective and Traceless Release of Small Molecules in β-Cells

[Image: see text] The loss of insulin-producing β-cells is the central pathological event in type 1 and 2 diabetes, which has led to efforts to identify molecules to promote β-cell proliferation, protection, and imaging. However, the lack of β-cell specificity of these molecules jeopardizes their th...

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Publicat a:J Am Chem Soc
Autors principals: Lee, Miseon, Maji, Basudeb, Manna, Debasish, Kahraman, Sevim, Elgamal, Ruth M., Small, Jonnell, Kokkonda, Praveen, Vetere, Amedeo, Goldberg, Jacob M., Lippard, Stephen J., Kulkarni, Rohit N., Wagner, Bridget K., Choudhary, Amit
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2020
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7146867/
https://ncbi.nlm.nih.gov/pubmed/32175731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c00099
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