CRISPR/Cas9-Mediated Foxp1 Silencing Restores Immune Surveillance in an Immunocompetent A20 Lymphoma Model

The interaction of lymphoma cells with their microenvironment has an important role in disease pathogenesis and is being actively pursued therapeutically using immunomodulatory drugs, including immune checkpoint inhibitors. Diffuse large B-cell lymphoma (DLBCL) is an aggressive high-grade disease th...

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Detalles Bibliográficos
Publicado en:Front Oncol
Main Authors: Felce, Suet Ling, Anderson, Amanda P., Maguire, Shaun, Gascoyne, Duncan M., Armstrong, Richard N., Wong, Kah Keng, Li, Demin, Banham, Alison H.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
Assuntos:
Oncology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7145990/
https://ncbi.nlm.nih.gov/pubmed/32309216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.00448
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