N-terminally truncated FOXP1 protein expression and alternate internal FOXP1 promoter usage in normal and malignant B cells

Strong FOXP1 protein expression is a poor risk factor in diffuse large B-cell lymphoma and has been linked to an activated B-cell-like subtype, which preferentially expresses short FOXP1 (FOXP1(S)) proteins. However, both short isoform generation and function are incompletely understood. Here we pro...

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Publicado no:Haematologica
Main Authors: Brown, Philip J., Gascoyne, Duncan M., Lyne, Linden, Spearman, Hayley, Felce, Suet Ling, McFadden, Nora, Chakravarty, Probir, Barrans, Sharon, Lynham, Steven, Calado, Dinis P., Ward, Malcolm, Banham, Alison H.
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004466/
https://ncbi.nlm.nih.gov/pubmed/27056922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2016.142141
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