Structure of the Cmr2 Subunit of the CRISPR-Cas RNA Silencing Complex

Cmr2 is the largest and an essential subunit of a CRISPR RNA-Cas protein complex (the Cmr complex) that cleaves foreign RNA to protect prokaryotes from invading genetic elements. Cmr2 is thought to be the catalytic subunit of the effector complex because of its N-terminal HD nuclease domain. Here ho...

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Detalhes bibliográficos
Publicado no:Structure
Main Authors: Cocozaki, Alexis I., Ramia, Nancy F., Shao, Yaming, Hale, Caryn R., Terns, Rebecca M., Terns, Michael P., Li, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4384425/
https://ncbi.nlm.nih.gov/pubmed/22405013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.01.018
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