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DNA and RNA interference mechanisms by CRISPR-Cas surveillance complexes

The CRISPR (clustered regularly interspaced short palindromic repeats)-Cas (CRISPR-associated) adaptive immune systems use small guide RNAs, the CRISPR RNAs (crRNAs), to mark foreign genetic material, e.g. viral nucleic acids, for degradation. Archaea and bacteria encode a large variety of Cas prote...

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Bibliografiske detaljer
Udgivet i:FEMS Microbiol Rev
Main Authors: Plagens, André, Richter, Hagen, Charpentier, Emmanuelle, Randau, Lennart
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5965380/
https://ncbi.nlm.nih.gov/pubmed/25934119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/femsre/fuv019
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