In vitro assembly and activity of an archaeal CRISPR-Cas type I-A Cascade interference complex

Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-CRISPR-associated (Cas) systems of type I use a Cas ribonucleoprotein complex for antiviral defense (Cascade) to mediate the targeting and degradation of foreign DNA. To address molecular features of the archaeal type I-A Cascade int...

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Détails bibliographiques
Auteurs principaux: Plagens, André, Tripp, Vanessa, Daume, Michael, Sharma, Kundan, Klingl, Andreas, Hrle, Ajla, Conti, Elena, Urlaub, Henning, Randau, Lennart
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2014
Sujets:
Nucleic Acid Enzymes
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005679/
https://ncbi.nlm.nih.gov/pubmed/24500198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku120
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