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Biogenesis pathways of RNA guides in archaeal and bacterial CRISPR-Cas adaptive immunity

CRISPR-Cas is an RNA-mediated adaptive immune system that defends bacteria and archaea against mobile genetic elements. Short mature CRISPR RNAs (crRNAs) are key elements in the interference step of the immune pathway. A CRISPR array composed of a series of repeats interspaced by spacer sequences ac...

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Detalhes bibliográficos
Publicado no:FEMS Microbiol Rev
Main Authors: Charpentier, Emmanuelle, Richter, Hagen, van der Oost, John, White, Malcolm F.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5965381/
https://ncbi.nlm.nih.gov/pubmed/25994611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/femsre/fuv023
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