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Functional interplay between DEAD-box RNA helicases Ded1 and Dbp1 in preinitiation complex attachment and scanning on structured mRNAs in vivo

RNA structures that impede ribosome binding or subsequent scanning of the 5′-untranslated region (5′-UTR) for the AUG initiation codon reduce translation efficiency. Yeast DEAD-box RNA helicase Ded1 appears to promote translation by resolving 5′-UTR structures, but whether its paralog, Dbp1, perform...

詳細記述

保存先:
書誌詳細
出版年:Nucleic Acids Res
主要な著者: Sen, Neelam Dabas, Gupta, Neha, K. Archer, Stuart, Preiss, Thomas, Lorsch, Jon R, Hinnebusch, Alan G
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7145680/
https://ncbi.nlm.nih.gov/pubmed/31299079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz595
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