ロード中...

Atomic structures of the RNA end-healing 5′-OH kinase and 2′,3′-cyclic phosphodiesterase domains of fungal tRNA ligase: conformational switches in the kinase upon binding of the GTP phosphate donor

Fungal tRNA ligase (Trl1) rectifies RNA breaks with 2′,3′-cyclic-PO(4) and 5′-OH termini. Trl1 consists of three catalytic modules: an N-terminal ligase (LIG) domain; a central polynucleotide kinase (KIN) domain; and a C-terminal cyclic phosphodiesterase (CPD) domain. Trl1 enzymes found in all human...

詳細記述

保存先:
書誌詳細
出版年:Nucleic Acids Res
主要な著者: Banerjee, Ankan, Goldgur, Yehuda, Schwer, Beate, Shuman, Stewart
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7145591/
https://ncbi.nlm.nih.gov/pubmed/31722405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz1049
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!