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Structural basis for the GTP specificity of the RNA kinase domain of fungal tRNA ligase
Fungal tRNA ligase (Trl1) is an essential enzyme that repairs RNA breaks with 2′,3′-cyclic-PO(4) and 5′-OH ends inflicted during tRNA splicing and non-canonical mRNA splicing in the fungal unfolded protein response. Trl1 is composed of C-terminal cyclic phosphodiesterase and central polynucleotide k...
Shranjeno v:
| izdano v: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5728400/ https://ncbi.nlm.nih.gov/pubmed/29165709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1159 |
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