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Distinctive kinetics and substrate specificities of plant and fungal tRNA ligases
Plant and fungal tRNA ligases are trifunctional enzymes that repair RNA breaks with 2′,3′-cyclic-PO(4) and 5′-OH ends. They are composed of cyclic phosphodiesterase (CPDase) and polynucleotide kinase domains that heal the broken ends to generate the 3′-OH, 2′-PO(4), and 5′-PO(4) required for sealing...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Cold Spring Harbor Laboratory Press
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3964908/ https://ncbi.nlm.nih.gov/pubmed/24554441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.043752.113 |
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