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Structural transitions in the RNA 7SK 5′ hairpin and their effect on HEXIM binding

7SK RNA, as part of the 7SK ribonucleoprotein complex, is crucial to the regulation of transcription by RNA-polymerase II, via its interaction with the positive transcription elongation factor P-TEFb. The interaction is induced by binding of the protein HEXIM to the 5′ hairpin (HP1) of 7SK RNA. Four...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Röder, Konstantin, Stirnemann, Guillaume, Dock-Bregeon, Anne-Catherine, Wales, David J, Pasquali, Samuela
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7145557/
https://ncbi.nlm.nih.gov/pubmed/31732748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz1071
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