Structural transitions in the RNA 7SK 5′ hairpin and their effect on HEXIM binding

7SK RNA, as part of the 7SK ribonucleoprotein complex, is crucial to the regulation of transcription by RNA-polymerase II, via its interaction with the positive transcription elongation factor P-TEFb. The interaction is induced by binding of the protein HEXIM to the 5′ hairpin (HP1) of 7SK RNA. Four...

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Bibliografiska uppgifter
I publikationen:Nucleic Acids Res
Huvudupphovsmän: Röder, Konstantin, Stirnemann, Guillaume, Dock-Bregeon, Anne-Catherine, Wales, David J, Pasquali, Samuela
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2020
Ämnen:
RNA and RNA-protein Complexes
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7145557/
https://ncbi.nlm.nih.gov/pubmed/31732748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz1071
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