The crystal structure of the 5΄ functional domain of the transcription riboregulator 7SK

In vertebrates, the 7SK RNA forms the scaffold of a complex, which regulates transcription pausing of RNA-polymerase II. By binding to the HEXIM protein, the complex comprising proteins LARP7 and MePCE captures the positive transcription elongation factor P-TEFb and prevents phosphorylation of pausi...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Martinez-Zapien, Denise, Legrand, Pierre, McEwen, Alastair G., Proux, Florence, Cragnolini, Tristan, Pasquali, Samuela, Dock-Bregeon, Anne-Catherine
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389472/
https://ncbi.nlm.nih.gov/pubmed/28082395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1351
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