HEXIM1 is a promiscuous double-stranded RNA-binding protein and interacts with RNAs in addition to 7SK in cultured cells

P-TEFb regulates eukaryotic gene expression at the level of transcription elongation, and is itself controlled by the reversible association of 7SK RNA and an RNA-binding protein HEXIM1 or HEXIM2. In an effort to determine the minimal region of 7SK needed to interact with HEXIM1 in vitro, we found t...

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Bibliographic Details
Main Authors: Li, Qintong, Cooper, Jeffrey J., Altwerger, Gary H., Feldkamp, Michael D., Shea, Madeline A., Price, David H.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2007
Subjects:
RNA
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885667/
https://ncbi.nlm.nih.gov/pubmed/17395637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm150
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