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New Peptide-Based Pharmacophore Activates 20S Proteasome
The proteasome is a pivotal element of controlled proteolysis, responsible for the catabolic arm of proteostasis. By inducing apoptosis, small molecule inhibitors of proteasome peptidolytic activities are successfully utilized in treatment of blood cancers. However, the clinical potential of proteas...
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| Publicado no: | Molecules |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7145288/ https://ncbi.nlm.nih.gov/pubmed/32235805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25061439 |
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