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Principles of RNA and nucleotide discrimination by the RNA processing enzyme RppH
All enzymes face a challenge of discriminating cognate substrates from similar cellular compounds. Finding a correct substrate is especially difficult for the Escherichia coli Nudix hydrolase RppH, which triggers 5′-end-dependent RNA degradation by removing orthophosphate from the 5′-diphosphorylate...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7144940/ https://ncbi.nlm.nih.gov/pubmed/31960065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa024 |
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