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Importance of a diphosphorylated intermediate for RppH-dependent RNA degradation
Deprotection of the 5′ end appears to be a universal mechanism for triggering the degradation of mRNA in bacteria and eukaryotes. In Escherichia coli, for example, converting the 5′ triphosphate of primary transcripts to a monophosphate accelerates cleavage at internal sites by the endonuclease RNas...
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| Veröffentlicht in: | RNA Biol |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6152431/ https://ncbi.nlm.nih.gov/pubmed/29619898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2018.1460995 |
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