Raltegravir (RAL) in neonates: Dosing, pharmacokinetics (PK), and safety in HIV-1 exposed neonates at risk of infection (IMPAACT P1110)

BACKGROUND: Adequate pharmacokinetic and safety data in neonates are lacking for most antiretroviral agents. Raltegravir is a selective HIV-1 integrase strand transfer inhibitor (INSTI) available in a granule formulation suitable for use in neonates and young infants as prophylaxis or treatment of H...

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Detalhes bibliográficos
Publicado no:J Acquir Immune Defic Syndr
Main Authors: Clarke, Diana F., Acosta, Edward P., Cababasay, Mae, Wang, Jiajia, Chain, Anne, Teppler, Hedy, Popson, Stephanie, Graham, Bobbie, Smith, Betsy, Hazra, Rohan, Calabrese, Kat, Bryson, Yvonne, Spector, Stephen A., Lommerse, Jos, Mirochnick, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7144886/
https://ncbi.nlm.nih.gov/pubmed/31913995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000002294
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