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EvoEF2: accurate and fast energy function for computational protein design

MOTIVATION: The accuracy and success rate of de novo protein design remain limited, mainly due to the parameter over-fitting of current energy functions and their inability to discriminate incorrect designs from correct designs. RESULTS: We developed an extended energy function, EvoEF2, for efficien...

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Bibliografiske detaljer
Udgivet i:Bioinformatics
Main Authors: Huang, Xiaoqiang, Pearce, Robin, Zhang, Yang
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7144094/
https://ncbi.nlm.nih.gov/pubmed/31588495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz740
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