Comparative neutralizing potencies of antibodies suggest conservation as well as mechanistic differences in human cytomegalovirus entry into epithelial and endothelial cells

Antibody neutralization of cytomegalovirus (CMV) entry into diverse cell types is a key consideration for development of vaccines and immunotherapeutics. CMV entry into fibroblasts differs significantly from entry into epithelial or endothelial cells: fibroblast entry is mediated by gB and gH/gL/gO,...

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Detalles Bibliográficos
Publicado en:Virol J
Main Authors: Qi, Ying, He, Li, Cui, Xiaohong, Hertel, Laura, Freed, Daniel C., Fu, Tong-Ming, Kauvar, Lawrence M., McVoy, Michael A., Ruan, Qiang
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2020
Assuntos:
Short Report
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7144056/
https://ncbi.nlm.nih.gov/pubmed/32268919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-020-01320-2
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