Comparative neutralizing potencies of antibodies suggest conservation as well as mechanistic differences in human cytomegalovirus entry into epithelial and endothelial cells

Antibody neutralization of cytomegalovirus (CMV) entry into diverse cell types is a key consideration for development of vaccines and immunotherapeutics. CMV entry into fibroblasts differs significantly from entry into epithelial or endothelial cells: fibroblast entry is mediated by gB and gH/gL/gO,...

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Publicat a:Virol J
Autors principals: Qi, Ying, He, Li, Cui, Xiaohong, Hertel, Laura, Freed, Daniel C., Fu, Tong-Ming, Kauvar, Lawrence M., McVoy, Michael A., Ruan, Qiang
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Short Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7144056/
https://ncbi.nlm.nih.gov/pubmed/32268919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-020-01320-2
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