Complement enhances in vitro neutralizing potency of antibodies to human cytomegalovirus glycoprotein B (gB) and immune sera induced by gB/MF59 vaccination

Human cytomegalovirus (HCMV) is the leading cause of in utero viral infection in the United States. Since congenital HCMV infection can lead to birth defects in newborns, developing a prophylactic vaccine is a high priority. One of the early experimental vaccines, composed of a recombinant glycoprot...

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Gepubliceerd in:NPJ Vaccines
Hoofdauteurs: Li, Fengsheng, Freed, Daniel C., Tang, Aimin, Rustandi, Richard R., Troutman, Matthew C., Espeseth, Amy S., Zhang, Ningyan, An, Zhiqiang, McVoy, Michael, Zhu, Hua, Ha, Sha, Wang, Dai, Adler, Stuart P., Fu, Tong-Ming
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5730571/
https://ncbi.nlm.nih.gov/pubmed/29263890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-017-0038-0
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