Complement enhances in vitro neutralizing potency of antibodies to human cytomegalovirus glycoprotein B (gB) and immune sera induced by gB/MF59 vaccination

Human cytomegalovirus (HCMV) is the leading cause of in utero viral infection in the United States. Since congenital HCMV infection can lead to birth defects in newborns, developing a prophylactic vaccine is a high priority. One of the early experimental vaccines, composed of a recombinant glycoprot...

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Bibliographic Details
Published in:	NPJ Vaccines
Main Authors:	Li, Fengsheng, Freed, Daniel C., Tang, Aimin, Rustandi, Richard R., Troutman, Matthew C., Espeseth, Amy S., Zhang, Ningyan, An, Zhiqiang, McVoy, Michael, Zhu, Hua, Ha, Sha, Wang, Dai, Adler, Stuart P., Fu, Tong-Ming
Format:	Artigo
Language:	Inglês
Published:	Nature Publishing Group UK 2017
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC5730571/ https://ncbi.nlm.nih.gov/pubmed/29263890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-017-0038-0
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Complement enhances in vitro neutralizing potency of antibodies to human cytomegalovirus glycoprotein B (gB) and immune sera induced by gB/MF59 vaccination

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