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Comparative neutralizing potencies of antibodies suggest conservation as well as mechanistic differences in human cytomegalovirus entry into epithelial and endothelial cells

Antibody neutralization of cytomegalovirus (CMV) entry into diverse cell types is a key consideration for development of vaccines and immunotherapeutics. CMV entry into fibroblasts differs significantly from entry into epithelial or endothelial cells: fibroblast entry is mediated by gB and gH/gL/gO,...

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Podrobná bibliografie
Vydáno v:	Virol J
Hlavní autoři:	Qi, Ying, He, Li, Cui, Xiaohong, Hertel, Laura, Freed, Daniel C., Fu, Tong-Ming, Kauvar, Lawrence M., McVoy, Michael A., Ruan, Qiang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BioMed Central 2020
Témata:	Short Report
On-line přístup:	https://ncbi.nlm.nih.gov/pmc/articles/PMC7144056/ https://ncbi.nlm.nih.gov/pubmed/32268919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-020-01320-2
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Comparative neutralizing potencies of antibodies suggest conservation as well as mechanistic differences in human cytomegalovirus entry into epithelial and endothelial cells

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