Phosphorylation independent eIF4E translational reprogramming of selective mRNAs determines tamoxifen resistance in breast cancer

Eukaryotic translation initiation factor 4E (eIF4E) selectively promotes translation of mRNAs with atypically long and structured 5′-UTRs and has been implicated in drug resistance. Through genome-wide transcriptome and translatome analysis we revealed eIF4E overexpression could promote cellular act...

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Detaylı Bibliyografya
Yayımlandı:Oncogene
Asıl Yazarlar: Gong, Chun, Tsoi, Ho, Mok, Ka Chun, Cheung, Jenny, Man, Ellen P. S., Fujino, Kazunari, Wong, Ashely, Lam, Eric W. F., Khoo, Ui-Soon
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7142019/
https://ncbi.nlm.nih.gov/pubmed/32066877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-1210-y
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