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DNA damage and eIF4G1 in breast cancer cells reprogram translation for survival and DNA repair mRNAs

The cellular response to DNA damage is mediated through multiple pathways that regulate and coordinate DNA repair, cell cycle arrest, and cell death. We show that the DNA damage response (DDR) induced by ionizing radiation (IR) is coordinated in breast cancer cells by selective mRNA translation medi...

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Detalhes bibliográficos
Main Authors: Badura, Michelle, Braunstein, Steve, Zavadil, Jiri, Schneider, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503184/
https://ncbi.nlm.nih.gov/pubmed/23112151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1203853109
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