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RASSF10 is frequently epigenetically inactivated in kidney cancer and its knockout promotes neoplasia in cancer prone mice

Kidney cancer incidences are rising globally, thereby fueling the demand for targeted therapies and precision medicine. In our previous work, we have identified and characterized the Ras-Association Domain Family encoding ten members that are often aberrantly expressed in human cancers. In this stud...

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Publicado en:Oncogene
Autores principales: Richter, Antje M., Woods, Michelle L., Küster, Miriam M., Walesch, Sara K., Braun, Thomas, Boettger, Thomas, Dammann, Reinhard H.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7142015/
https://ncbi.nlm.nih.gov/pubmed/32047266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-1195-6
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