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The tumor suppressor RASSF1A induces the YAP1 target gene ANKRD1 that is epigenetically inactivated in human cancers and inhibits tumor growth

The Hippo pathway regulates organ size, growth and comprises several tumor related factors, including the oncoprotein YAP1 and the tumor suppressor RASSF1A. RASSF1A is frequently epigenetically inactivated in cancer. In our study, we analyzed the effect of RASSF1A on the function of YAP1. Expression...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Oncotarget
मुख्य लेखकों: Jiménez, Adriana P., Traum, Annalena, Boettger, Thomas, Hackstein, Holger, Richter, Antje M., Dammann, Reinhard H.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Impact Journals LLC 2017
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5687617/
https://ncbi.nlm.nih.gov/pubmed/29179447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18177
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