The tumor suppressor RASSF1A induces the YAP1 target gene ANKRD1 that is epigenetically inactivated in human cancers and inhibits tumor growth

The Hippo pathway regulates organ size, growth and comprises several tumor related factors, including the oncoprotein YAP1 and the tumor suppressor RASSF1A. RASSF1A is frequently epigenetically inactivated in cancer. In our study, we analyzed the effect of RASSF1A on the function of YAP1. Expression...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Jiménez, Adriana P., Traum, Annalena, Boettger, Thomas, Hackstein, Holger, Richter, Antje M., Dammann, Reinhard H.
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2017
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5687617/
https://ncbi.nlm.nih.gov/pubmed/29179447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18177
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