Frequent epigenetic inactivation of RASSF2 in thyroid cancer and functional consequences

BACKGROUND: The Ras association domain family (RASSF) encodes for distinct tumor suppressors and several members are frequently silenced in human cancer. In our study, we analyzed the role of RASSF2, RASSF3, RASSF4, RASSF5A, RASSF5C and RASSF6 and the effectors MST1, MST2 and WW45 in thyroid carcino...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Schagdarsurengin, Undraga, Richter, Antje M, Hornung, Juliane, Lange, Cornelia, Steinmann, Katrin, Dammann, Reinhard H
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2010
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956732/
https://ncbi.nlm.nih.gov/pubmed/20920251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-264
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