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Dictating Thermodynamic Control through Tethering: Applications to Stereoselective Bis-Spiroketal Synthesis

Approaches to stereocontrol that invoke thermodynamic control fail when two or more potential products are energetically similar, but rational structural perturbations can be employed to break the energetic degeneracy and provide selective transformations. This manuscript illustrates that tethering...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Asari, Austin H., Floreancig, Paul E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7141965/
https://ncbi.nlm.nih.gov/pubmed/31991022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201916270
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