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Stereoselective Synthesis of Spirooxindole Amides through Nitrile Hydrozirconation

[Image: see text] Spirooxindole amides can be prepared by the intramolecular addition of functionalized indoles into acyliminium ions that are accessed from nitriles by hydrozirconation and acylation. The stereochemical outcome at the quaternary center was controlled by the steric bulk of the substi...

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Bibliografski detalji
Glavni autori: Lu, Chunliang, Xiao, Qing, Floreancig, Paul E.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980567/
https://ncbi.nlm.nih.gov/pubmed/20961073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol102246d
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