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Stereoselective Synthesis of Spirooxindole Amides through Nitrile Hydrozirconation
[Image: see text] Spirooxindole amides can be prepared by the intramolecular addition of functionalized indoles into acyliminium ions that are accessed from nitriles by hydrozirconation and acylation. The stereochemical outcome at the quaternary center was controlled by the steric bulk of the substi...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2980567/ https://ncbi.nlm.nih.gov/pubmed/20961073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol102246d |
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