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Gating and selectivity mechanisms for the lysosomal K(+) channel TMEM175
Transmembrane protein 175 (TMEM175) is a K(+)-selective ion channel expressed in lysosomal membranes, where it establishes a membrane potential essential for lysosomal function and its dysregulation is associated with the development of Parkinson’s Disease. TMEM175 is evolutionarily distinct from al...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7141809/ https://ncbi.nlm.nih.gov/pubmed/32228865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.53430 |
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