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Structural basis for ion selectivity in TMEM175 K(+) channels
The TMEM175 family constitutes recently discovered K(+)channels that are important for autophagosome turnover and lysosomal pH regulation and are associated with the early onset of Parkinson Disease. TMEM175 channels lack a P-loop selectivity filter, a hallmark of all known K(+) channels, raising th...
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| Publicado en: | eLife |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
eLife Sciences Publications, Ltd
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7176437/ https://ncbi.nlm.nih.gov/pubmed/32267231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.53683 |
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