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Base Editors: Modular Tools for the Introduction of Point Mutations in Living Cells
Base editors are a new family of programmable genome editing tools that fuse ssDNA (single stranded DNA) modifying enzymes to catalytically inactive CRISPR-associated (Cas) endonucleases to induce highly efficient single base changes. With dozens of base editors now reported, it is apparent that the...
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| Publicado no: | Emerg Top Life Sci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7141416/ https://ncbi.nlm.nih.gov/pubmed/32270050 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/etls20190088 |
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