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Morphogen Delivery by Osteoconductive Nanoparticles Instructs Stromal Cell Spheroid Phenotype

Mesenchymal stem/stromal cells (MSCs) exhibit a rapid loss in osteogenic phenotype upon removal of osteoinductive cues, as commonly occurs during transplantation. Osteogenic differentiation can be more effectively but not fully maintained by aggregating MSCs into spheroids. Therefore, the developmen...

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Detalhes bibliográficos
Publicado no:Adv Biosyst
Main Authors: Whitehead, Jacklyn, Kothambawala, Alefia, Leach, J. Kent
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7141413/
https://ncbi.nlm.nih.gov/pubmed/32270027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adbi.201900141
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