Engineering Fibrin Hydrogels to Promote the Wound Healing Potential of Mesenchymal Stem Cell Spheroids

Mesenchymal stem cells (MSCs) secrete endogenous factors such as vascular endothelial growth factor (VEGF) and prostaglandin E2 (PGE(2)) that promote angiogenesis, modulate the inflammatory microenvironment, and stimulate wound repair, and MSC spheroids secrete more trophic factors than dissociated,...

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Udgivet i:Acta Biomater
Main Authors: Murphy, Kaitlin C., Whitehead, Jacklyn, Zhou, Dejie, Ho, Steve S., Leach, J. Kent
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5682213/
https://ncbi.nlm.nih.gov/pubmed/28987783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2017.10.007
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