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Morphogen Delivery by Osteoconductive Nanoparticles Instructs Stromal Cell Spheroid Phenotype

Mesenchymal stem/stromal cells (MSCs) exhibit a rapid loss in osteogenic phenotype upon removal of osteoinductive cues, as commonly occurs during transplantation. Osteogenic differentiation can be more effectively but not fully maintained by aggregating MSCs into spheroids. Therefore, the developmen...

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Pubblicato in:Adv Biosyst
Autori principali: Whitehead, Jacklyn, Kothambawala, Alefia, Leach, J. Kent
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7141413/
https://ncbi.nlm.nih.gov/pubmed/32270027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adbi.201900141
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