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Tunneling Nanotubes Mediate the Expression of Senescence Markers in Mesenchymal Stem/Stromal Cell Spheroids

The therapeutic potential of mesenchymal stem/stromal cells (MSCs) is limited by acquired senescence following prolonged culture expansion and high passage numbers. However, the degree of cell senescence is dynamic, and cell-cell communication is critical to promote cell survival. MSC spheroids exhi...

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Publicado en:Stem Cells
Autores principales: Whitehead, Jacklyn, Zhang, Jiali, Harvestine, Jenna N., Kothambawala, Alefia, Liu, Gang-yu, Leach, J. Kent
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6954984/
https://ncbi.nlm.nih.gov/pubmed/31298767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.3056
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