Mesenchymal Stem Cell Spheroids Retain Osteogenic Phenotype Through α(2)β(1) Signaling

The induction of mesenchymal stem cells (MSCs) toward the osteoblastic lineage using osteogenic supplements prior to implantation is one approach under examination to enhance their bone-forming potential. MSCs rapidly lose their induced phenotype upon removal of the soluble stimuli; however, their b...

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Détails bibliographiques
Publié dans:Stem Cells Transl Med
Auteurs principaux: Murphy, Kaitlin C., Hoch, Allison I., Harvestine, Jenna N., Zhou, Dejie, Leach, J. Kent
Format: Artigo
Langue:Inglês
Publié: AlphaMed Press 2016
Sujets:
Enabling Technologies for Cell-Based Clinical Translation
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4996446/
https://ncbi.nlm.nih.gov/pubmed/27365484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2015-0412
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