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Lysine Acetylation Reshapes the Downstream Signaling Landscape of Vav1 in Lymphocytes

Vav1 works both as a catalytic Rho GTPase activator and an adaptor molecule. These functions, which are critical for T cell development and antigenic responses, are tyrosine phosphorylation-dependent. However, it is not known whether other posttranslational modifications can contribute to the regula...

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Bibliografische gegevens
Gepubliceerd in:Cells
Hoofdauteurs: Rodríguez-Fdez, Sonia, Fernández-Nevado, Lucía, Lorenzo-Martín, L. Francisco, Bustelo, Xosé R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7140538/
https://ncbi.nlm.nih.gov/pubmed/32143292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9030609
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