Apelin Affects the Progression of Osteoarthritis by Regulating VEGF-Dependent Angiogenesis and miR-150-5p Expression in Human Synovial Fibroblasts

Synovium-induced angiogenesis is central to osteoarthritis (OA) pathogenesis and thus a promising therapeutic target. The adipokine apelin (APLN) is involved in both OA pathogenesis and angiogenesis. We examined the role of APLN in synovium-induced angiogenesis by investigating the crosstalk between...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Wang, Yu-Han, Kuo, Shu-Jui, Liu, Shan-Chi, Wang, Shih-Wei, Tsai, Chun-Hao, Fong, Yi-Chin, Tang, Chih-Hsin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7140420/
https://ncbi.nlm.nih.gov/pubmed/32131466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9030594
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