TGF-β1 enhances FOXO3 expression in human synovial fibroblasts by inhibiting miR-92a through AMPK and p38 pathways

Osteoarthritis (OA) is an age-related disease marked by synovial inflammation and cartilage destruction arising from synovitis, joint swelling and pain. OA therapy that targets the synovium is a promising strategy for mitigating the symptoms and disease progression. Altered activity of the transform...

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Podrobná bibliografie
Vydáno v:Aging (Albany NY)
Hlavní autoři: Kuo, Shu-Jui, Liu, Shan-Chi, Huang, Yuan-Li, Tsai, Chun-Hao, Fong, Yi-Chin, Hsu, Horng-Chaung, Tang, Chih-Hsin
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals 2019
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6628998/
https://ncbi.nlm.nih.gov/pubmed/31232696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102038
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