Apelin enhances IL-1β expression in human synovial fibroblasts by inhibiting miR-144-3p through the PI3K and ERK pathways

Much data suggests intersecting activities between the adipokine apelin (APLN) and the pathologic processes of obesity and osteoarthritis (OA), with APLN modulating cartilage, synovium, bone, and various immune cell activities. The synovium plays an important role in the pathogenesis of OA. We inves...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Chang, Ting-Kuo, Wang, Yu-Han, Kuo, Shu-Jui, Wang, Shih-Wei, Tsai, Chun-Hao, Fong, Yi-Chin, Wu, Nan-Lin, Liu, Shan-Chi, Tang, Chih-Hsin
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7288923/
https://ncbi.nlm.nih.gov/pubmed/32420902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103195
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